Description

2-(2-Trifluoromethyl-Phenyl)-Cyclopropanecarboxylic Acid is a high-value, fluorinated cyclopropane derivative that serves as a critical synthetic intermediate. Its unique structure, featuring a cyclopropane ring and a trifluoromethylphenyl group, makes it an essential building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of new drug candidates, particularly for incorporating the cyclopropane and trifluoromethyl motifs which can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atoms contribute to improved lipophilicity and biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced materials with specific chemical resistance or surface properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry for the synthesis of chiral ligands or metal-organic frameworks (MOFs) due to its rigid, three-dimensional structure.
• Fluorine Chemistry Studies: A valuable substrate for investigating new fluorination reactions and studying the influence of the CF3 group on reaction pathways and molecular conformation.

Basic Information

Product Name	2-(2-Trifluoromethyl-Phenyl)-Cyclopropanecarboxylic Acid
CAS No.	1187933-13-6
Molecular Formula	C11H9F3O2
Molecular Weight	230.18 g/mol
Synonyms	2-[2-(Trifluoromethyl)phenyl]cyclopropane-1-carboxylic acid; 2-(2-Trifluoromethylphenyl)cyclopropanecarboxylic acid; 2-(α,α,α-Trifluoro-o-tolyl)cyclopropanecarboxylic Acid; Cyclopropanecarboxylic acid, 2-[2-(trifluoromethyl)phenyl]-; o-(Trifluoromethyl)phenylcyclopropanecarboxylic acid
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Production follows current Good Manufacturing Practice (cGMP) principles where applicable, and every batch is analyzed to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥97% by HPLC), physical characteristics, and impurity profiles is provided with each shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider holding under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.