Description

2,3,4-Trifluoro-Benzamidine Hydrochloride is a high-purity fluorinated benzamidine derivative, supplied as its stable hydrochloride salt. This compound serves as a critical pharmaceutical intermediate and versatile building block in organic synthesis, enabling the introduction of a trifluoromethyl-substituted amidine moiety. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of protease inhibitors, kinase inhibitors, and other small molecule drug candidates.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and pesticides that leverage the trifluoromethyl group for enhanced bioactivity and stability.
• Chemical Biology & Proteomics: Serves as a precursor for affinity probes and activity-based protein profiling (ABPP) reagents targeting serine hydrolases and other enzymes.
• Material Science: Potential monomer or functionalization agent for creating specialty polymers with unique electronic or surface properties.
• Organic Synthesis: Versatile reagent for constructing heterocycles, such as imidazoles and pyrimidines, via cyclization reactions.

Basic Information

Product Name	2,3,4-Trifluoro-Benzamidine Hydrochloride
CAS No.	1187929-42-5
Molecular Formula	C7H6ClF3N2
Molecular Weight	210.58 g/mol
Synonyms	2,3,4-Trifluorobenzamidine hydrochloride; 2,3,4-Trifluorobenzenecarboximidamide hydrochloride; Benzenecarboximidamide, 2,3,4-trifluoro-, hydrochloride (1:1); 2,3,4-Trifluoro-benzenecarboximidamide monohydrochloride
EINECS	Contact for details

Quality Control

Our 2,3,4-Trifluoro-Benzamidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy. We provide comprehensive Certificates of Analysis (COA) detailing all specifications, ensuring traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.