Description

2,3,4,5,6-Pentafluorobenzimidamide Hydrochloride is a high-purity, fluorinated benzimidamide derivative supplied as its hydrochloride salt, a key building block in advanced organic synthesis. This compound is valued for its role in introducing the pentafluorophenyl moiety, which can significantly alter the electronic properties, metabolic stability, and bioavailability of target molecules. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly those targeting kinases or requiring enhanced lipophilicity and metabolic stability.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the pentafluorophenyl group can improve activity and environmental persistence profiles.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating specialized ligands used in catalysis or as molecular probes in chemical biology.
• Material Science Precursor: Employed in the synthesis of fluorinated organic compounds for advanced materials, such as liquid crystals or polymers with specific electronic properties.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses serving the life sciences sector, enabling the production of complex, fluorinated target molecules.

Basic Information

Product Name	2,3,4,5,6-Pentafluorobenzimidamide Hydrochloride
CAS No.	1187927-16-7
Molecular Formula	C7H3ClF5N2
Molecular Weight	248.56 g/mol
Synonyms	2,3,4,5,6-Pentafluorobenzimidamide HCl; Pentafluorobenzamidine Hydrochloride; 2,3,4,5,6-Pentafluorobenzenecarboximidamide Hydrochloride; 2,3,4,5,6-Pentafluorobenzamidine Hydrochloride; Benzenecarboximidamide, 2,3,4,5,6-pentafluoro-, hydrochloride (1:1); Pentafluorobenzamidine HCl Salt
EINECS	Contact for details

Quality Control

Our 2,3,4,5,6-Pentafluorobenzimidamide Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under anhydrous conditions to maintain product integrity and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.