Description

tert-Butyl 2-Bromo-4,5-Dimethylphenylcarbamate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active molecules. This compound is valued for its role as a key building block, enabling the precise introduction of a brominated, dimethyl-substituted aromatic moiety with a protected amine group. It is primarily utilized by research and development teams and process chemists in the pharmaceutical and agrochemical industries for constructing novel drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Organic Synthesis Reagent: Serves as a versatile reagent in academic and industrial laboratories for constructing complex organic molecules, especially in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Material Science Research: A potential monomer or precursor for developing specialty polymers and advanced organic materials with specific electronic or structural properties.
• Chemical Biology Probe Development: Used to create molecular probes for studying biological pathways and protein functions due to its reactive bromine handle and protected amine.

Basic Information

Product Name	tert-Butyl 2-Bromo-4,5-Dimethylphenylcarbamate
CAS No.	1187926-96-0
Molecular Formula	C13H18BrNO2
Molecular Weight	300.19 g/mol
Synonyms	Carbamic acid, N-(2-bromo-4,5-dimethylphenyl)-, 1,1-dimethylethyl ester; 2-Bromo-4,5-dimethylphenyl tert-butylcarbamate; tert-Butyl (2-bromo-4,5-dimethylphenyl)carbamate; N-(tert-Butoxycarbonyl)-2-bromo-4,5-dimethylaniline; Boc-2-Bromo-4,5-dimethylaniline; BOC-2-Br-4,5-Dimethylaniline; 2-Bromo-4,5-dimethylaniline N-Boc derivative
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Bromo-4,5-Dimethylphenylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.