Description

5-Bromo-N,2-Dimethylaniline, Hcl CAS NO 1187386-32-8 is a halogenated aniline derivative, specifically the hydrochloride salt of a substituted aniline. This compound is a valuable high-purity chemical intermediate essential for advanced organic synthesis. It is primarily utilized by pharmaceutical research and development teams and fine chemical manufacturers for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides, leveraging its halogenated aniline core structure.
• Dye and Pigment Manufacturing: Serves as a precursor for the production of specialized azo dyes and organic pigments.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and advanced polymeric materials.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for creating complex amine derivatives.
• Academic & Contract Research: A critical reagent for medicinal chemistry programs and process development in academic and CRO/CMO settings.

Basic Information

Product Name	5-Bromo-N,2-Dimethylaniline, Hcl
CAS No.	1187386-32-8
Molecular Formula	C8H11BrN • HCl
Molecular Weight	236.55 g/mol (Free base: 200.08 g/mol)
Synonyms	5-Bromo-2,N-Dimethylaniline Hydrochloride; 1-Bromo-5-(dimethylamino)-2-methylbenzene Hydrochloride; 2-Methyl-5-bromo-N-methylaniline Hydrochloride; 5-Bromo-2-methyl-N-methylaniline HCl; N,2-Dimethyl-5-bromoaniline Hydrochloride; 5-Bromo-N-methyl-o-toluidine Hydrochloride; 5-Bromo-2-methyl-N-methylbenzenamine Hydrochloride
EINECS	Contact for details

Quality Control

Our 5-Bromo-N,2-Dimethylaniline, Hcl is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.