Description

5-Bromopyridazin-3-Amine is a versatile brominated heterocyclic building block of significant importance in modern synthetic chemistry. Its reactive amine and halogen substituents make it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in drug discovery and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, leveraging the pyridazine core for bioactivity.
• Material Science Research: Acts as a building block for creating functional organic materials, such as ligands for catalysts or components in organic electronics.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Cross-Coupling Reactions: The bromine atom is amenable to various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for carbon-carbon and carbon-heteroatom bond formation.
• Heterocyclic Library Synthesis: A fundamental scaffold for generating diverse compound libraries in medicinal chemistry for high-throughput screening.

Basic Information

Product Name	5-Bromopyridazin-3-Amine
CAS No.	1187237-00-8
Molecular Formula	C4H4BrN3
Molecular Weight	173.99 g/mol
Synonyms	3-Amino-5-bromopyridazine; 5-Bromo-3-pyridazinamine; 5-Bromopyridazin-3-ylamine; 5-Bromo-1,2-diazin-3-amine; 5-Bromo-3-aminopyridazine; 3-Pyridazinamine, 5-bromo-; 5-Bromopyridazin-3-amine (principal IUPAC name)
EINECS	Contact for details

Quality Control

Our 5-Bromopyridazin-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.