Description

3-Chloro-6-(4-Piperidyloxy)Pyridazine is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1185536-63-3. This heterocyclic compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily sought by research institutions and pharmaceutical development companies engaged in medicinal chemistry and process scale-up.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Process Chemistry & Scale-Up: Serves as a defined starting material for the development and optimization of scalable synthetic routes under GMP conditions.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of clinical trial materials.
• Academic Research: Employed in university and institutional labs for exploratory organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	3-Chloro-6-(4-Piperidyloxy)Pyridazine
CAS No.	1185536-63-3
Molecular Formula	C9H12ClN3O
Molecular Weight	213.66 g/mol
Synonyms	3-Chloro-6-(piperidin-4-yloxy)pyridazine; 6-(4-Piperidyloxy)-3-chloropyridazine; 3-Chloro-6-(4-piperidinoloxy)pyridazine; 1185536-63-3; 4-[(3-Chloropyridazin-6-yl)oxy]piperidine; Piperidine, 4-[(3-chloro-6-pyridazinyl)oxy]-; 3-Chloro-6-(piperidin-4-yloxy)pyridazine
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-6-(4-Piperidyloxy)Pyridazine adheres to stringent quality protocols suitable for pharmaceutical R&D. Each batch is characterized and tested to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with data from advanced analytical techniques, including HPLC, NMR, and MS. Our quality system supports development under ICH guidelines, and custom purity grades (e.g., >98%, >99%) are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.