Description

3-Chloro-6-(Piperidin-4-Yloxy)-Pyridazine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with significant synthetic utility. This compound is valued for its role as a key building block in the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor research.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry Development: Serves as a key starting material (KSM) or advanced intermediate in the scale-up and optimization of API synthesis routes.
• Biochemical Tool Compound: Potential use in the development of probes for biological target identification and validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services.

Basic Information

Item	Detail
Product Name	3-Chloro-6-(Piperidin-4-Yloxy)-Pyridazine Hydrochloride
CAS No.	1185307-15-6
Molecular Formula	C9H13Cl2N3O
Molecular Weight	250.13 g/mol
Synonyms	3-Chloro-6-(4-piperidinyloxy)pyridazine hydrochloride; 3-Chloro-6-(piperidin-4-yloxy)pyridazine HCl; 1185307-15-6; 6-(Piperidin-4-yloxy)-3-chloropyridazine hydrochloride; 3-Chloro-6-(4-piperidyloxy)pyridazine hydrochloride; 3-Chloro-6-(1-piperidinyloxy)pyridazine hydrochloride (isomeric); Pyridazine, 3-chloro-6-(4-piperidinyloxy)-, hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Chloro-6-(Piperidin-4-Yloxy)-Pyridazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator to prevent degradation upon exposure to air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.