Description

5-Chloro-2-Ethyl-3-Methyl-1-Benzofuran-7-Amine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1185301-77-2. This compound is valued for its role as a critical building block in the synthesis of complex organic molecules, particularly in medicinal chemistry. It is essential for research and development laboratories and production facilities focused on creating novel active pharmaceutical ingredients (APIs) and fine chemicals. The product is supplied with stringent quality control to ensure batch-to-batch consistency for demanding synthesis workflows.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Organic Synthesis Building Block: Serves as a versatile starting material for constructing complex benzofuran-based heterocyclic compounds.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals for agrochemical and material science applications.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations requiring high-purity, well-characterized intermediates for client projects.

Basic Information

Product Name	5-Chloro-2-Ethyl-3-Methyl-1-Benzofuran-7-Amine Hydrochloride
CAS No.	1185301-77-2
Molecular Formula	C₁₁H₁₃Cl₂NO
Molecular Weight	246.13 g/mol
Synonyms	7-Amino-5-chloro-2-ethyl-3-methylbenzofuran hydrochloride; 5-Chloro-2-ethyl-3-methyl-7-benzofuranamine hydrochloride; 1185301-77-2; 5-Chloro-2-ethyl-3-methylbenzofuran-7-amine HCl; 2-Ethyl-3-methyl-5-chloro-7-aminobenzofuran hydrochloride
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Ethyl-3-Methyl-1-Benzofuran-7-Amine Hydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.