Description

(2,3-Dihydro-Benzo[1,4]Dioxin-5-Yl)-(4-Hydroxymethyl-Piperidin-1-Yl)-Methanone CAS NO 1184761-02-1 is a high-purity, advanced pharmaceutical intermediate featuring a benzodioxin-piperidine hybrid scaffold. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system and cardiovascular disorders. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for neurological and cardiovascular applications.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Process Chemistry Development: Serves as a standard or starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Biochemical Tool Compound: Employed in vitro and in vivo to study biological pathways and receptor interactions.
• Custom Synthesis Building Block: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	(2,3-Dihydro-Benzo[1,4]Dioxin-5-Yl)-(4-Hydroxymethyl-Piperidin-1-Yl)-Methanone
CAS No.	1184761-02-1
Molecular Formula	C15H19NO4
Molecular Weight	277.32 g/mol
Synonyms	1-[(2,3-Dihydro-1,4-benzodioxin-5-yl)carbonyl]-4-(hydroxymethyl)piperidine; 4-(Hydroxymethyl)-1-(2,3-dihydro-1,4-benzodioxine-5-carbonyl)piperidine; (2,3-Dihydrobenzo[b][1,4]dioxin-5-yl)(4-(hydroxymethyl)piperidin-1-yl)methanone; 1,4-Benzodioxan-5-yl 4-(hydroxymethyl)piperidin-1-yl ketone; 1184761-02-1; 5-[(4-Hydroxymethyl-1-piperidinyl)carbonyl]-2,3-dihydro-1,4-benzodioxin
EINECS	Contact for details

Quality Control

Our (2,3-Dihydro-Benzo[1,4]Dioxin-5-Yl)-(4-Hydroxymethyl-Piperidin-1-Yl)-Methanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with research and development grade standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.