Description

4-Amino-Tetrahydro-2H-Pyran-4-Carboxamide is a high-value, functionalized heterocyclic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both an amino and a carboxamide group on a saturated tetrahydropyran ring, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disease targets.
• Agrochemical Synthesis: Used in the design and production of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.
• Academic and Institutional Research: A valuable compound for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	4-Amino-Tetrahydro-2H-Pyran-4-Carboxamide
CAS No.	1183378-09-7
Molecular Formula	C6H12N2O2
Molecular Weight	144.17 g/mol
Synonyms	4-Aminotetrahydropyran-4-carboxamide; 4-Aminooxane-4-carboxamide; 4-Amino-tetrahydro-2H-pyran-4-carboxylic acid amide; 4-Aminotetrahydro-2H-pyran-4-carboxylic acid amide; 4-Amino-4-carbamoyltetrahydropyran; Tetrahydro-2H-pyran-4-carboxamide, 4-amino-; 4-Amino-4-carbamoyloxane
EINECS	Contact for details

Quality Control

Our 4-Amino-Tetrahydro-2H-Pyran-4-Carboxamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.