Description

1-(2-Chlorophenyl)Butan-1-Amine is a specialized chiral amine building block with a chlorinated aromatic moiety. This compound is valued for its role as a key intermediate in the synthesis of complex, biologically active molecules, offering a defined stereocenter for precise structural control. It is primarily needed by pharmaceutical R&D and fine chemical synthesis teams developing new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) targets.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where specific stereochemistry influences biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Research: Employed in academic and industrial laboratories for methodological studies in organic and medicinal chemistry.
• Fine Chemical Production: A building block for the manufacture of specialty chemicals, dyes, and functional materials.

Basic Information

Product Name	1-(2-Chlorophenyl)Butan-1-Amine
CAS No.	1182824-37-8
Molecular Formula	C10H14ClN
Molecular Weight	183.68 g/mol
Synonyms	(±)-1-(2-Chlorophenyl)butan-1-amine; 1-Amino-1-(2-chlorophenyl)butane; 2-Chloro-α-propylbenzylamine; 1-(2-Chlorophenyl)-1-butanamine; Butan-1-amine, 1-(2-chlorophenyl)-; α-Butyl-2-chlorobenzylamine; (RS)-1-(2-Chlorophenyl)butan-1-amine
EINECS	Contact for details

Quality Control

Our 1-(2-Chlorophenyl)Butan-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.