Description

3-Chloro-2-Methylbiphenyl-3-Carboxylic Acid is a high-purity biphenyl derivative carboxylic acid, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its functionalized aromatic structure, which provides a versatile scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists in the fine chemical and life science industries who require reliable, high-quality building blocks for drug discovery and material science applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, leveraging its halogenated biphenyl core.
• Material Science Research: Serves as a precursor for functionalized organic materials, including liquid crystals and organic semiconductors.
• Chemical Research & Development: Employed as a versatile synthon in academic and industrial laboratories for method development and exploring new chemical spaces.
• Custom Synthesis & Contract Manufacturing: A starting material for the custom synthesis of complex, target-specific molecules for client projects.

Basic Information

Product Name	3-Chloro-2-Methylbiphenyl-3-Carboxylic Acid
CAS No.	1181321-00-5
Molecular Formula	C14H11ClO2
Molecular Weight	246.69 g/mol
Synonyms	3'-Chloro-2'-methyl-[1,1'-biphenyl]-3-carboxylic acid; 3-Chloro-2-methylbiphenyl-3-carboxylic acid; 2-Methyl-3-chlorobiphenyl-3-carboxylic Acid; [1,1'-Biphenyl]-3-carboxylic acid, 3'-chloro-2'-methyl-; 3-Chloro-2-methyl-3-biphenylcarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-2-Methylbiphenyl-3-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.