Description

3-Chloro-2-[(2,2-Difluoroethyl)Sulfanyl]Aniline is a specialized aromatic amine derivative featuring a chloro-substituted aniline core and a difluoroethylthio side chain. This compound matters as a high-value pharmaceutical intermediate and agrochemical building block, enabling the synthesis of novel active ingredients. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Serves as a crucial building block for creating advanced herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Used in the research and preparation of specialized ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Employed as a monomer or functionalization agent in the synthesis of advanced polymers and functional materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme inhibition.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up campaigns.

Basic Information

Item	Details
Product Name	3-Chloro-2-[(2,2-Difluoroethyl)Sulfanyl]Aniline
CAS No.	1179075-22-9
Molecular Formula	C8H8ClF2NS
Molecular Weight	223.67 g/mol
Synonyms	3-Chloro-2-[(2,2-difluoroethyl)thio]aniline; 2-Amino-6-chlorobenzene-1-thiol, 2,2-difluoroethyl ether; 1-Chloro-2-[(2,2-difluoroethyl)sulfanyl]-6-aminobenzene; 3-Chloro-2-(2,2-difluoroethylthio)aniline; Benzenamine, 3-chloro-2-[(2,2-difluoroethyl)thio]-; 1179075-22-9; 3-Chloro-2-(2,2-difluoroethylsulfanyl)phenylamine
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-[(2,2-Difluoroethyl)Sulfanyl]Aniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all specified parameters. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.