Description

(4-Amino-Chroman-4-Yl)-Methanol is a versatile chiral amino alcohol building block of significant interest in advanced organic synthesis. Its value lies in its unique fused bicyclic chroman structure, which serves as a key pharmacophore and chiral scaffold for developing novel active compounds. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for constructing complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and other therapeutic areas.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its chroman core for bioactive molecule design.
• Asymmetric Synthesis: Serves as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Chemical Biology Probes: Utilized in medicinal chemistry to create molecular probes for studying enzyme mechanisms and biological pathways.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and advanced materials.

Basic Information

Product Name	(4-Amino-Chroman-4-Yl)-Methanol
CAS No.	1178618-15-9
Molecular Formula	C10H13NO2
Molecular Weight	179.22 g/mol
Synonyms	4-(Aminomethyl)-4-hydroxy-chroman; 4-Hydroxy-4-(aminomethyl)-2,3-dihydro-1-benzopyran; 4-Amino-4-hydroxymethylchroman; 4-(Hydroxymethyl)-4-aminochroman; 4-Aminochroman-4-methanol; (4-Amino-4-chromanyl)methanol; 4-Amino-4-(hydroxymethyl)chroman
EINECS	Contact for details

Quality Control

Our (4-Amino-Chroman-4-Yl)-Methanol is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling and chiral analysis to confirm enantiomeric purity where applicable. A detailed Certificate of Analysis (COA) documenting identity, purity, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Chiral Purity (Chiral HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.