Description

6-Chloro-3-(Tributylstannyl)-Imidazo[1,2-A]Pyridine is a specialized organotin reagent featuring a fused imidazopyridine heterocycle, designed for advanced cross-coupling reactions in synthetic chemistry. This compound is critical for constructing complex molecular architectures where precise carbon-carbon bond formation is required. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for synthesizing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) or possessing antiviral properties.
• Agrochemical Research: Used to create new active ingredients for crop protection agents by enabling the introduction of the chlorinated imidazopyridine moiety.
• Material Science: Serves as a precursor for functionalized organic semiconductors or ligands in catalytic systems due to its electron-rich heterocyclic structure.
• Stille Cross-Coupling Reactions: Acts as a versatile organotin donor reagent for palladium-catalyzed coupling with aryl, heteroaryl, or alkenyl halides/triflates.
• Chemical Biology Probe Development: Utilized to label or modify biomolecules for studying biological pathways and protein interactions.
• Ligand Synthesis: Employed in the preparation of complex nitrogen-containing ligands for transition metal catalysis.

Basic Information

Product Name	6-Chloro-3-(Tributylstannyl)-Imidazo[1,2-A]Pyridine
CAS No.	1177264-56-0
Molecular Formula	C19H31ClN2Sn
Molecular Weight	441.62 g/mol
Synonyms	6-Chloro-3-(tributylstannyl)imidazo[1,2-a]pyridine; Tributyl(6-chloroimidazo[1,2-a]pyridin-3-yl)stannane; 6-Chloro-3-tributylstannylimidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 6-chloro-3-(tributylstannyl)-; 1177264-56-0; 6-Chloro-3-(tributyltin)imidazo[1,2-a]pyridine; 3-Tributylstannyl-6-chloroimidazo[1,2-a]pyridine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Every batch is characterized by NMR (1H, 13C), HPLC, and elemental analysis (Tin content) to confirm identity, purity, and stoichiometry. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry, and well-ventilated place. This material is hygroscopic (moisture-sensitive) and easily oxidized. Allow the sealed container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Off-white to light yellow solid or oil
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Tin Content (Analysis)	26.5 - 27.5 %
Water Content (KF)	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.