Description

2-(3,4-Dihydroxyphenyl)-3,7-Dihydroxy-4H-Chromen-4-One Hydrate is a polyphenolic flavonoid compound, specifically a hydrated form of luteolin. This high-purity chemical is valued for its potent antioxidant and bioactive properties, making it a critical reference standard and active ingredient in advanced research and development. It is essential for industries focused on pharmaceuticals, nutraceuticals, and life science research, where precise molecular structure and purity are paramount for efficacy and reproducibility.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control, method validation, and regulatory compliance in drug development and manufacturing.
• Nutraceutical & Dietary Supplement Formulation: Serves as a key bioactive ingredient in supplements targeting oxidative stress, inflammation, and metabolic health due to its strong antioxidant profile.
• Biochemical & Life Science Research: Employed in in vitro and in vivo studies to investigate mechanisms of action related to cell signaling, anti-inflammatory pathways, and neuroprotective effects.
• Cosmeceutical Active Ingredient: Incorporated into advanced skincare formulations for its anti-aging and protective properties against environmental stressors.
• Analytical Chemistry: Utilized as a high-purity standard for calibrating analytical instruments like HPLC and LC-MS in compound identification and quantification.

Basic Information

Product Name	2-(3,4-Dihydroxyphenyl)-3,7-Dihydroxy-4H-Chromen-4-One Hydrate
CAS No.	1174865-69-0
Molecular Formula	C15H10O6 · xH2O
Molecular Weight	286.24 g/mol (anhydrous basis)
Synonyms	Luteolin Hydrate; 3',4',5,7-Tetrahydroxyflavone Hydrate; 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-chromenone Hydrate; Digitoflavone Hydrate; Cyanidenon 147 Hydrate; Luteolol Hydrate
EINECS	Contact for details

Quality Control

Every batch of our 2-(3,4-Dihydroxyphenyl)-3,7-Dihydroxy-4H-Chromen-4-One Hydrate is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the stringent requirements for research and industrial use. A detailed Certificate of Analysis (COA) including results for assay, related substances, and residual solvents is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Yellow to yellowish-brown powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	Reported on COA
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.