Description

n-[(1R,2R)-2-Amino-1,2-Diphenylethyl]-N'-(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)-Thiourea is a sophisticated chiral thiourea derivative that serves as a key intermediate in advanced organic synthesis and pharmaceutical research. Its molecular architecture, featuring a glucopyranosyl moiety and a chiral diamine backbone, makes it a valuable ligand precursor and building block for the development of asymmetric catalysts and biologically active compounds. This high-purity specialty chemical is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, carbohydrate chemistry, and enantioselective synthesis.

Application

• Asymmetric Catalysis: Serves as a precursor for chiral thiourea organocatalysts used in enantioselective C-C bond-forming reactions and other stereocontrolled transformations.
• Pharmaceutical Intermediate: A critical building block in the research and development of novel glycosylated drug candidates and targeted therapeutics.
• Carbohydrate Chemistry Research: Used in the study of glycosylation reactions and the synthesis of complex glycoconjugates due to its protected glucopyranosyl group.
• Chiral Ligand Synthesis: Employed for the preparation of specialized ligands for metal complexes used in asymmetric hydrogenation and other catalytic processes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes to study enzyme inhibition and carbohydrate-protein interactions.
• Academic & Industrial R&D: A valuable reagent for method development and discovery chemistry in both university laboratories and corporate R&D centers.

Basic Information

Product Name	n-[(1R,2R)-2-Amino-1,2-Diphenylethyl]-N'-(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)-Thiourea
CAS No.	1174340-49-8
Molecular Formula	C31H37N3O9S
Molecular Weight	627.71 g/mol
Synonyms	(1R,2R)-N-[(2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl)carbamothioyl]-1,2-diphenylethane-1,2-diamine; 1-[(1R,2R)-2-Amino-1,2-diphenylethyl]-3-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)thiourea; Chiral Glucosyl Thiourea Derivative; Acetylated Glucopyranosyl Thiourea; (R,R)-DPEN-derived Glucosyl Thiourea
EINECS	Contact for details

Quality Control

Our production of n-[(1R,2R)-2-Amino-1,2-Diphenylethyl]-N'-(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)-Thiourea adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification (NMR, IR, MS). Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.