Description

n-[(1S,2S)-2-(Dimethylamino)Cyclohexyl]-N'-[[(1R,4As,10Ar)-1,2,3,4,4A,9,10,10A-Octahydro-1,4A-Dimethyl-7-(1-Methylethyl)-1-Phenanthrenyl]Methyl]-Thiourea is a sophisticated chiral thiourea derivative with a complex, multi-cyclic structure designed for high-affinity molecular recognition. This compound is of significant interest in advanced pharmaceutical research and development, particularly as a potent and selective chemical probe or intermediate for targeting specific biological pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in drug discovery, especially in areas requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel therapeutic agents, particularly for central nervous system (CNS) or anti-inflammatory targets.
• Chemical Biology Research: Used as a high-affinity ligand or probe in biochemical assays to study protein-protein interactions, enzyme inhibition, or receptor binding.
• Asymmetric Catalysis: Potential application as an organocatalyst or chiral auxiliary in stereoselective synthetic transformations due to its rigid thiourea and amine motifs.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.
• Medicinal Chemistry Optimization: Provides a scaffold for structure-activity relationship (SAR) studies to optimize pharmacokinetic and pharmacodynamic properties of lead compounds.

Basic Information

Product Name	n-[(1S,2S)-2-(Dimethylamino)Cyclohexyl]-N'-[[(1R,4As,10Ar)-1,2,3,4,4A,9,10,10A-Octahydro-1,4A-Dimethyl-7-(1-Methylethyl)-1-Phenanthrenyl]Methyl]-Thiourea
CAS No.	1173373-69-7
Molecular Formula	C29H47N3S
Molecular Weight	469.77 g/mol
Synonyms	(1S,2S)-N1-(((1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-(propan-2-yl)-1-phenanthryl)methyl)-N2-(2-(dimethylamino)cyclohexyl)carbamimidothioic acid diamide; Thiourea, N-[(1S,2S)-2-(dimethylamino)cyclohexyl]-N'-[[(1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenyl]methyl]-; CAS 1173373-69-7; (S,S)-DMCH Thiourea derivative; Abietic acid-derived thiourea; Chiral thiourea ligand; Steroidal thiourea compound.
EINECS	Contact for details

Quality Control

Our n-[(1S,2S)-2-(Dimethylamino)Cyclohexyl]-N'-[[(1R,4As,10Ar)-1,2,3,4,4A,9,10,10A-Octahydro-1,4A-Dimethyl-7-(1-Methylethyl)-1-Phenanthrenyl]Methyl]-Thiourea is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.