Description

5-(Trifluoromethyl)-1-Benzothiophene-2-Carbohydrazide is a high-purity, advanced pharmaceutical intermediate characterized by its benzothiophene core and reactive carbohydrazide functional group. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with enhanced metabolic stability and binding affinity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule therapeutics, particularly kinase inhibitors and anti-inflammatory agents.
• Agrochemical Research: Used in developing new generation herbicides and fungicides, leveraging the trifluoromethyl group for improved lipophilicity and bioactivity.
• Material Science: Serves as a monomer or functionalizing agent for creating specialty polymers with unique electronic or surface properties.
• Chemical Synthesis: The reactive hydrazide moiety makes it a versatile reagent for constructing heterocyclic compounds like pyrazoles and triazoles via condensation reactions.
• Ligand Synthesis: Employed in the development of chelating ligands for catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	5-(Trifluoromethyl)-1-Benzothiophene-2-Carbohydrazide
CAS No.	1171927-43-7
Molecular Formula	C10H7F3N2OS
Molecular Weight	260.24 g/mol
Synonyms	5-(Trifluoromethyl)benzo[b]thiophene-2-carbohydrazide; 1-Benzothiophene-2-carbohydrazide, 5-(trifluoromethyl)-; 5-Trifluoromethyl-1-benzothiophene-2-carboxylic acid hydrazide; 5-(Trifluoromethyl)benzothiophene-2-carboxylic hydrazide; 2-Hydrazinylcarbonyl-5-(trifluoromethyl)benzothiophene
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)-1-Benzothiophene-2-Carbohydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to store the material under an inert atmosphere for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.