Description

1-Isobutyl-3-Pyrrolidin-2-Yl-1H-Pyrazole is a high-purity, advanced pharmaceutical intermediate with a unique heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is essential for medicinal chemists and process development scientists in pharmaceutical R&D and manufacturing who require reliable, high-quality intermediates to accelerate drug discovery and development pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and development services for the global pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for studying novel heterocyclic chemistry and biological activity.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	1-Isobutyl-3-Pyrrolidin-2-Yl-1H-Pyrazole
CAS No.	1170410-77-1
Molecular Formula	C11H19N3
Molecular Weight	193.29 g/mol
Synonyms	1-(2-Methylpropyl)-3-(pyrrolidin-2-yl)-1H-pyrazole; 3-(Pyrrolidin-2-yl)-1-isobutyl-1H-pyrazole; 1H-Pyrazole, 1-(2-methylpropyl)-3-(2-pyrrolidinyl)-; 1-Isobutyl-3-(2-pyrrolidinyl)-1H-pyrazole; Pyrrolidin-2-yl-pyrazole derivative
EINECS	Contact for details

Quality Control

Our 1-Isobutyl-3-Pyrrolidin-2-Yl-1H-Pyrazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We can support development with custom purity grades and analytical data packages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.