Description

3-Butynyl Methanethiosulfonate CAS NO 1170318-61-2 is a specialized organosulfur compound featuring a reactive methanethiosulfonate group linked to a terminal alkyne moiety. This unique bifunctional structure makes it a valuable intermediate for chemical synthesis, particularly in bioconjugation and materials science. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds and functionalized materials.

Application

• Bioconjugation Reagent: Used for site-specific protein and peptide labeling via cysteine residues, enabling the study of protein structure, function, and interactions.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates with tailored biological activity.
• Polymer Modification: Employed to introduce alkyne functional groups into polymer backbones for subsequent "click chemistry" reactions, such as copper-catalyzed azide-alkyne cycloaddition (CuAAC).
• Agrochemical Synthesis: Acts as a precursor in the development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Probe Development: Utilized to create activity-based probes for studying enzyme mechanisms and profiling in complex biological systems.
• Surface Functionalization: Applied to modify material surfaces (e.g., gold, silicon) with alkyne-terminated monolayers for sensor and device fabrication.

Basic Information

Product Name	3-Butynyl Methanethiosulfonate
CAS No.	1170318-61-2
Molecular Formula	C5H8O2S2
Molecular Weight	164.24 g/mol
Synonyms	But-3-yn-1-yl methanesulfonothioate; Methanesulfonothioic acid S-(3-butynyl) ester; 3-Butyn-1-yl methanethiosulfonate; 3-Butynyl methanesulfonothioate; MTSEA-alkyne derivative; Propargyl homologue of MTSEA
EINECS	Contact for details

Quality Control

Our 3-Butynyl Methanethiosulfonate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced chemical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to prevent degradation and moisture absorption. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.