Description

3-(n-(2,4-Difluorophenyl)Carbamoyl)Prop-2-Enoic Acid is a high-purity, specialized organic intermediate featuring a difluorophenyl carbamoyl moiety. This compound is critical for the synthesis of advanced pharmaceutical ingredients and agrochemicals, where its unique fluorinated structure imparts desirable biological activity and metabolic stability. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance lipophilicity and target binding.
• Chemical Biology & Proteomics: Serves as a versatile scaffold or linker for creating chemical probes, enzyme inhibitors, and activity-based protein profiling (ABPP) reagents.
• Material Science Precursor: Potential monomer or additive in the synthesis of specialty polymers and advanced materials requiring fluorinated components for specific thermal or chemical resistance properties.
• Contract Research & Development (CRO/CMO): Supplied to research organizations and custom synthesis facilities for client-directed projects and scale-up activities.

Basic Information

Product Name	3-(n-(2,4-Difluorophenyl)Carbamoyl)Prop-2-Enoic Acid
CAS No.	1164538-71-9
Molecular Formula	C10H7F2NO3
Molecular Weight	227.16 g/mol
Synonyms	3-[(2,4-Difluorophenyl)carbamoyl]acrylic acid; 2-Propenoic acid, 3-[[(2,4-difluorophenyl)amino]carbonyl]-; (E)-3-((2,4-Difluorophenyl)carbamoyl)acrylic acid; N-(2,4-Difluorophenyl)-3-carboxyacrylamide; 2,4-DFPCA; Acrylic acid, 3-[(2,4-difluorophenyl)carbamoyl]-
EINECS	Contact for details

Quality Control

Every batch of 3-(n-(2,4-Difluorophenyl)Carbamoyl)Prop-2-Enoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, with typical purity levels exceeding 97% (HPLC). A Certificate of Analysis (COA) detailing specific batch results for assay, related substances, and residual solvents is available upon request. Our quality commitment supports compliance in GMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.