Description

n-(5-Acetyl-6-[2-(Dimethylamino)Vinyl]-2-Oxo-2H-Pyran-3-Yl)-3-(Trifluoromethyl)Benzenecarboxamide is a sophisticated organic compound featuring a pyranone core functionalized with acetyl, dimethylaminovinyl, and a trifluoromethylbenzamide group. This unique molecular architecture makes it a valuable advanced intermediate for the synthesis of complex molecules, particularly in pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for constructing novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and development of new drug candidates, especially those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability.
• Agrochemical Research: Used in the synthesis of novel active ingredients for crop protection, where the trifluoromethyl group can impart favorable biological activity and environmental persistence.
• Material Science Precursor: Potential use in the development of organic electronic materials or specialty polymers due to its conjugated system and functional handles.
• Chemical Biology Probe: Acts as a scaffold for developing molecular probes to study enzyme function or cellular pathways in academic and industrial research settings.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services to the pharmaceutical and biotechnology industries.

Basic Information

Product Name	n-(5-Acetyl-6-[2-(Dimethylamino)Vinyl]-2-Oxo-2H-Pyran-3-Yl)-3-(Trifluoromethyl)Benzenecarboxamide
CAS No.	1164529-66-1
Molecular Formula	C19H17F3N2O4
Molecular Weight	394.35 g/mol
Synonyms	3-(Trifluoromethyl)-N-[5-acetyl-6-[(E)-2-(dimethylamino)ethenyl]-2-oxo-2H-pyran-3-yl]benzamide; 3-(Trifluoromethyl)benzoic acid [5-acetyl-6-[(E)-2-(dimethylamino)vinyl]-2-oxo-2H-pyran-3-yl]amide; (E)-N-(5-Acetyl-6-(2-(dimethylamino)vinyl)-2-oxo-2H-pyran-3-yl)-3-(trifluoromethyl)benzamide; 1164529-66-1; AGN-PC-0JSTPJ; AKOS025247064; BDBM50389359; SMR001252777
EINECS	Contact for details

Quality Control

Our n-(5-Acetyl-6-[2-(Dimethylamino)Vinyl]-2-Oxo-2H-Pyran-3-Yl)-3-(Trifluoromethyl)Benzenecarboxamide is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports your R&D and scale-up processes with reliable, traceable materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be light-sensitive and hygroscopic; therefore, handling under an inert atmosphere is recommended for long-term storage or when opening the primary container.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.