Description

1,2-Benzenediamine, 4-Bromo-N2-(Tetrahydro-2H-Pyran-4-Yl)- is a specialized brominated benzenediamine derivative with a tetrahydro-2H-pyran-4-yl substituent, serving as a high-value intermediate in advanced organic synthesis. Its molecular architecture makes it a critical building block for constructing complex heterocyclic systems and functionalized aromatic compounds. This compound is primarily utilized by research institutions and pharmaceutical development teams focused on medicinal chemistry and material science applications.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and plant growth regulators requiring specific halogenated amine functionalities.
• Material Science: Building block for advanced polymers, liquid crystals, and organic electronic materials where its bromine and amine groups enable precise molecular tuning.
• Chemical Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) and as a ligand precursor in organometallic chemistry.
• Dye and Pigment Intermediate: Used in the synthesis of specialized azo dyes and high-performance pigments for industrial applications.

Basic Information

Product Name	1,2-Benzenediamine, 4-Bromo-N2-(Tetrahydro-2H-Pyran-4-Yl)-
CAS No.	1162697-10-0
Molecular Formula	C11H15BrN2O
Molecular Weight	271.16 g/mol
Synonyms	4-Bromo-N2-(tetrahydro-2H-pyran-4-yl)benzene-1,2-diamine; 4-Bromo-1,2-phenylenediamine N2-(tetrahydropyran-4-yl) derivative; 4-Bromo-1,2-diaminobenzene tetrahydro-2H-pyran-4-yl adduct; 1,2-Diamino-4-bromobenzene N-(oxan-4-yl) derivative; Brominated benzenediamine-THP intermediate; CAS 1162697-10-0; 4-Bromo-N-(oxan-4-yl)benzene-1,2-diamine
EINECS	Contact for details

Quality Control

Our 1,2-Benzenediamine, 4-Bromo-N2-(Tetrahydro-2H-Pyran-4-Yl)- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing including HPLC for purity, NMR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.