Description

7-(Tributylstannyl)Isoquinoline is a specialized organotin reagent featuring a stannyl group attached to the isoquinoline heterocycle. This compound matters as a versatile building block in advanced organic synthesis, particularly for cross-coupling reactions like the Stille coupling, enabling the efficient construction of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those containing the isoquinoline pharmacophore.
• Stille Cross-Coupling Reagent: Used in palladium-catalyzed reactions to form carbon-carbon bonds, facilitating the introduction of the isoquinoline moiety into target molecules.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Materials Science & OLED Development: Serves as a building block for creating organic semiconductors, light-emitting materials, and other advanced functional materials.
• Ligand Synthesis: Used to prepare novel organometallic catalysts and ligands for asymmetric synthesis.
• Chemical Biology Probes: Facilitates the labeling and study of biological systems through bioconjugation strategies.

Basic Information

Product Name	7-(Tributylstannyl)Isoquinoline
CAS No.	1161975-56-9
Molecular Formula	C21H33NSn
Molecular Weight	418.19 g/mol
Synonyms	7-(Tributylstannyl)isoquinoline; Tributyl(7-isoquinolyl)stannane; 7-Isoquinolinyltributyltin; 7-(Tributyltin)isoquinoline; Stannane, tributyl-7-isoquinolinyl-; 7-Tributylstannyl-isoquinoline; 7-(SnBu3)Isoquinoline; 7-(Tri-n-butylstannyl)isoquinoline
EINECS	Contact for details

Quality Control

Our 7-(Tributylstannyl)Isoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹⁹Sn) and HPLC analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee the material meets your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended long-term storage at 2-8°C. Keep away from strong acids and oxidizing agents. Handle in a well-ventilated fume hood using appropriate personal protective equipment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
¹H NMR Purity	Conforms
Tin (Sn) Content	~28.4% (Theoretical)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.