Description

2-(4-Fluorophenyl)-6-(Trifluoromethyl)-4,5-Dihydropyridazin-3(2H)-One is a high-value, fluorinated heterocyclic compound that serves as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, featuring both phenyl and trifluoromethyl substituents on a dihydropyridazinone core, makes it an essential building block for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecules with enhanced biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and synthesis of new drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used in developing next-generation herbicides, fungicides, and insecticides, where the fluorine atoms improve metabolic stability and membrane permeability.
• Chemical Biology Probe: Serves as a scaffold for designing molecular probes to study enzyme function and biological pathways.
• Material Science Precursor: Potential intermediate for synthesizing specialty polymers or liquid crystals with specific electronic properties.
• Contract Research & Development (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client projects.

Basic Information

Product Name	2-(4-Fluorophenyl)-6-(Trifluoromethyl)-4,5-Dihydropyridazin-3(2H)-One
CAS No.	1161004-70-1
Molecular Formula	C11H8F4N2O
Molecular Weight	260.19 g/mol
Synonyms	2-(4-Fluorophenyl)-6-(trifluoromethyl)-4,5-dihydro-3(2H)-pyridazinone; 6-(Trifluoromethyl)-2-(4-fluorophenyl)-4,5-dihydro-3(2H)-pyridazinone; 2-(p-Fluorophenyl)-6-(trifluoromethyl)-4,5-dihydropyridazin-3(2H)-one; 1161004-70-1; 4,5-Dihydro-2-(4-fluorophenyl)-6-(trifluoromethyl)-3(2H)-pyridazinone
EINECS	Contact for details

Quality Control

Our production of 2-(4-Fluorophenyl)-6-(Trifluoromethyl)-4,5-Dihydropyridazin-3(2H)-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, critical for sensitive R&D and scale-up processes. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support customer needs for regulatory filings, including those for pharmaceuticals (following ICH Q7 guidelines) and agrochemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.