Description

3-Bromo-2-Chloro-5-Nitroanisole is a high-purity halogenated nitroanisole derivative, serving as a critical advanced intermediate in organic synthesis. Its value lies in providing a versatile, multi-functional aromatic scaffold for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and process development scientists in fine chemical manufacturing, where it is used to introduce specific bromo, chloro, and nitro substituents for targeted activity.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules requiring specific halogenated aromatic cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where its substitution pattern can influence biological activity.
• Material Science Research: Serves as a precursor for functionalized organic materials, including liquid crystals and specialty polymers.
• Dye and Pigment Intermediate: Employed in the synthesis of complex azo dyes and other colored compounds due to its nitro and halogen functional groups.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for creating biaryl structures common in many advanced chemicals.
• Chemical Research & Development: A valuable reagent for method development and exploring new reaction pathways in academic and industrial R&D laboratories.

Basic Information

Product Name	3-Bromo-2-Chloro-5-Nitroanisole
CAS No.	1160574-48-0
Molecular Formula	C7H5BrClNO3
Molecular Weight	266.48 g/mol
Synonyms	1-Bromo-2-chloro-3-methoxy-5-nitrobenzene; 2-Chloro-3-bromo-5-nitroanisole; Benzene, 1-bromo-2-chloro-3-methoxy-5-nitro-; 3-Methoxy-2-chloro-5-nitrobenzyl bromide (incorrect but common search variant); Anisole, 3-bromo-2-chloro-5-nitro-; 5-Nitro-3-bromo-2-chloroanisole
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Chloro-5-Nitroanisole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.