Description

3-[(3-Methoxyphenyl)Sulfonyl]Azetidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a sulfonylated azetidine core. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel small-molecule therapeutics targeting a range of diseases. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in central nervous system (CNS) and oncology research.
• Medicinal Chemistry R&D: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its unique azetidine scaffold.
• Protease Inhibitor Development: The sulfonamide moiety makes it a valuable precursor for developing enzyme inhibitors.
• Chemical Biology Probes: Serves as a core structure for creating tool compounds to study biological pathways.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects.
• Academic Research: Used in university and institutional labs for exploratory synthetic and pharmacological studies.

Basic Information

Product Name	3-[(3-Methoxyphenyl)Sulfonyl]Azetidine Hydrochloride
CAS No.	1160245-62-4
Molecular Formula	C10H14ClNO3S
Molecular Weight	263.74 g/mol
Synonyms	Azetidine, 3-[(3-methoxyphenyl)sulfonyl]-, hydrochloride (1:1); 3-(3-Methoxyphenylsulfonyl)azetidine hydrochloride; 3-(m-Anisylsulfonyl)azetidine HCl; 1-(3-Methoxyphenylsulfonyl)azetidin-3-amine hydrochloride; Azetidine-3-sulfonic acid (3-methoxyphenyl)amide hydrochloride
EINECS	Contact for details

Quality Control

Our 3-[(3-Methoxyphenyl)Sulfonyl]Azetidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) are available for every shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary after opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.