Description

n-Ethyltetrahydro-2H-Pyran-4-Amine Hydrochloride is a high-purity organic salt compound, primarily utilized as a key synthetic intermediate in advanced pharmaceutical research and development. Its value lies in its role as a versatile building block for constructing complex nitrogen-containing heterocycles, which are crucial scaffolds in modern medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for API synthesis and novel compound libraries.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic amine structure.
• Chemical Research & Development: Serves as a versatile precursor for creating diverse chemical libraries in medicinal chemistry and high-throughput screening.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science Precursor: Potential use in the synthesis of functional polymers and advanced organic materials.

Basic Information

Product Name	n-Ethyltetrahydro-2H-Pyran-4-Amine Hydrochloride
CAS No.	1158623-65-4
Molecular Formula	C7H16ClNO
Molecular Weight	165.66 g/mol
Synonyms	4-(Ethylamino)tetrahydro-2H-pyran hydrochloride; N-Ethyl-4-aminotetrahydropyran hydrochloride; Tetrahydropyran-4-amine, N-ethyl-, hydrochloride; 1-Ethyl-1,2,3,6-tetrahydropyridin-4-amine hydrochloride (tautomeric form); 4-(Ethylamino)oxane hydrochloride; THP-4-amine, N-ethyl-, HCl; Ethyl-tetrahydropyran-4-yl-amine hydrochloride
EINECS	Contact for details

Quality Control

Our n-Ethyltetrahydro-2H-Pyran-4-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) that detail specifications including assay (HPLC), related substances, residual solvents, and other critical parameters. Our quality commitment supports applications requiring high standards, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.