Description

4-Methylamino-Tetrahydro-Pyran-4-Carboxylic Acid is a versatile chiral building block and intermediate of significant importance in modern synthetic organic chemistry. Its unique structural motif, featuring both a carboxylic acid and a methylamino group on a tetrahydro-pyran ring, makes it a valuable scaffold for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries. It serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals requiring specific stereochemistry.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel therapeutic agents, including potential central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where its specific stereochemistry can influence biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Research: Employed in academic and industrial R&D for method development and the construction of complex molecular libraries.
• Fine Chemical Production: Acts as a building block for specialty chemicals, flavors, and fragrances requiring high purity and defined configuration.

Basic Information

Product Name	4-Methylamino-Tetrahydro-Pyran-4-Carboxylic Acid
CAS No.	1157932-08-5
Molecular Formula	C8H15NO3
Molecular Weight	173.21 g/mol
Synonyms	4-(Methylamino)tetrahydro-2H-pyran-4-carboxylic acid; 4-Methylaminotetrahydropyran-4-carboxylic Acid; 4-(Methylamino)oxane-4-carboxylic acid; 2H-Pyran-4-carboxylic acid, 4-(methylamino)tetrahydro-; 4-MATPC; 4-Methylamino-THP-4-carboxylic acid; 4-(N-Methylamino)tetrahydropyran-4-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 4-Methylamino-Tetrahydro-Pyran-4-Carboxylic Acid is produced under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure compliance with exacting customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.