Description

2-(Tetrahydro-Pyran-4-Yl)-2H-Pyrazol-3-Ylamine is a high-purity, heterocyclic amine building block of significant interest in advanced organic synthesis. Its unique fused pyran-pyrazole structure makes it a valuable intermediate for constructing complex molecular architectures. This compound is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel small-molecule drug candidates, particularly in central nervous system (CNS) and metabolic disorder therapeutic areas.
• Agrochemical Research: Serves as a core structural component in the synthesis of new pesticides and herbicides, leveraging its heterocyclic scaffold for bioactivity.
• Chemical Biology Probe Development: Used to create specialized molecular probes and tool compounds for studying biological pathways and target validation.
• Material Science Precursor: Acts as a building block for synthesizing specialty polymers, ligands for catalysis, or advanced organic materials with specific electronic properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced drug discovery and custom synthesis projects for global clients.

Basic Information

Product Name	2-(Tetrahydro-Pyran-4-Yl)-2H-Pyrazol-3-Ylamine
CAS No.	1157012-67-3
Molecular Formula	C8H13N3O
Molecular Weight	167.21 g/mol
Synonyms	2-(Oxan-4-yl)-2H-pyrazol-3-amine; 2-(Tetrahydropyran-4-yl)-2H-pyrazol-3-amine; 3-Amino-2-(tetrahydro-2H-pyran-4-yl)-2H-pyrazole; 2H-Pyrazol-3-amine, 2-(tetrahydro-2H-pyran-4-yl)-; 1157012-67-3; 2-(THP-4-yl)-2H-pyrazol-3-ylamine; 2-(Tetrahydro-2H-pyran-4-yl)-2H-pyrazol-3-amine
EINECS	Contact for details

Quality Control

Our 2-(Tetrahydro-Pyran-4-Yl)-2H-Pyrazol-3-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.