Description

8-Chloro-5-Methylchroman is a specialized organic compound belonging to the chroman class, serving as a key synthetic intermediate in advanced chemical manufacturing. Its value lies in its unique halogenated and alkylated structure, which provides a versatile scaffold for constructing more complex molecules in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its chroman core structure.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a precursor for developing advanced electron-transport or host materials in OLED device fabrication.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.
• Flavor and Fragrance Chemistry: Utilized in the synthesis of complex aroma chemicals and flavoring agents due to its oxygen-containing heterocyclic structure.
• Academic and Industrial Research: A valuable reagent for methodological studies in organic chemistry, including cyclization and functionalization reactions.

Basic Information

Product Name	8-Chloro-5-Methylchroman
CAS No.	1154740-71-2
Molecular Formula	C10H11ClO
Molecular Weight	182.65 g/mol
Synonyms	8-Chloro-5-methyl-3,4-dihydro-2H-1-benzopyran; 5-Methyl-8-chlorochromane; 8-Chloro-5-methyl-2H-chromene; 8-Chloro-5-methyl-3,4-dihydro-2H-chromene; 8-Chloro-5-methylchroman-4-ol (related derivative); 8-Cl-5-Me-chroman
EINECS	Contact for details

Quality Control

Our 8-Chloro-5-Methylchroman is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Custom synthesis and purification to meet specific client requirements (e.g., >98%, >99% purity) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.