Description

6-[4-(2-Hydroxyethyl)Piperazine-1-Carbonyl]-2-Methyl-2,3-Dihydropyridazin-3-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique piperazine-dihydropyridazinone hybrid structure. This compound is of significant value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, especially for central nervous system (CNS) and anti-inflammatory targets.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry & Scale-Up: Serves as a critical intermediate in the pilot-scale and commercial-scale synthesis of proprietary APIs.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for the study of heterocyclic chemistry and the development of new synthetic methodologies.

Basic Information

Product Name	6-[4-(2-Hydroxyethyl)Piperazine-1-Carbonyl]-2-Methyl-2,3-Dihydropyridazin-3-One
CAS No.	1153231-27-6
Molecular Formula	C13H20N4O3
Molecular Weight	280.32 g/mol
Synonyms	2-Methyl-6-[4-(2-hydroxyethyl)-1-piperazinyl]carbonyl-2,3-dihydro-3(2H)-pyridazinone; 2-Methyl-6-[[4-(2-hydroxyethyl)-1-piperazinyl]carbonyl]-2,3-dihydro-3(2H)-pyridazinone; 6-({4-[2-Hydroxyethyl]piperazin-1-yl}carbonyl)-2-methyl-2,3-dihydropyridazin-3-one; 2-Methyl-6-(4-(2-hydroxyethyl)piperazine-1-carbonyl)-2,3-dihydropyridazin-3(2H)-one
EINECS	Contact for details

Quality Control

Our 6-[4-(2-Hydroxyethyl)Piperazine-1-Carbonyl]-2-Methyl-2,3-Dihydropyridazin-3-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.