Description

n-(4-Bromobenzyl)-3-Fluorobenzylamine is a high-purity (97%) organic building block featuring both bromo and fluoro substituents on aromatic rings, making it a versatile intermediate for advanced synthesis. This compound is valued for its role in facilitating cross-coupling reactions and introducing specific pharmacophores into target molecules. It is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the halogenated aromatic structure for bioactivity.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Intermediate in the production of advanced polymers and liquid crystals where fluorine and bromine atoms impart specific electronic and physical properties.
• Cross-Coupling Reactions: The bromobenzyl moiety makes it an excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Chemical Biology Probes: Used to synthesize fluorescent tags or affinity probes for studying biological systems and protein interactions.

Basic Information

Product Name	n-(4-Bromobenzyl)-3-Fluorobenzylamine, 97%
CAS No.	1152540-59-4
Molecular Formula	C14H13BrFN
Molecular Weight	294.16 g/mol
Synonyms	1-[(4-Bromophenyl)methyl]-3-fluorobenzylamine; 3-Fluoro-N-[(4-bromophenyl)methyl]benzenemethanamine; N-[(4-Bromobenzyl)]-3-fluorobenzylamine; Benzenemethanamine, 3-fluoro-N-[(4-bromophenyl)methyl]-; 4-Bromo-N-(3-fluorobenzyl)benzylamine; (4-Bromobenzyl)(3-fluorobenzyl)amine; 3-Fluorobenzyl-(4-bromobenzyl)amine
EINECS	Contact for details

Quality Control

Our n-(4-Bromobenzyl)-3-Fluorobenzylamine is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the specified 97% minimum assay. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.