Description

Methyl 4-Fluorotetrahydro-2H-Pyran-4-Carboxylate CAS NO 1150617-60-9 is a high-value fluorinated heterocyclic building block, specifically a fluorinated tetrahydropyran derivative. This compound is critical for introducing both fluorine and a constrained, oxygen-containing ring system into target molecules, which can significantly alter their physicochemical and biological properties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, metabolic diseases, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom and tetrahydropyran moiety can enhance bioavailability and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty monomers or polymers with tailored properties for advanced materials.
• Fluorine Chemistry Building Block: A versatile starting material for further functionalization in exploratory fluorine chemistry and library synthesis for high-throughput screening.

Basic Information

Product Name	Methyl 4-Fluorotetrahydro-2H-Pyran-4-Carboxylate
CAS No.	1150617-60-9
Molecular Formula	C7H11FO3
Molecular Weight	162.16 g/mol
Synonyms	Methyl 4-fluorooxane-4-carboxylate; 4-Fluorotetrahydro-2H-pyran-4-carboxylic acid methyl ester; 4-Fluoro-tetrahydropyran-4-carboxylic acid methyl ester; Methyl 4-fluorotetrahydropyran-4-carboxylate; 4-Fluoro-tetrahydro-2H-pyran-4-carboxylic acid methyl ester; 4-Fluorotetrahydropyran-4-carboxylic Acid Methyl Ester; Methyl 4-fluoro-4-tetrahydropyrancarboxylate
EINECS	Contact for details

Quality Control

Our Methyl 4-Fluorotetrahydro-2H-Pyran-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.