Description

2,2,6,6-Tetramethylpiperidinylzinc Chloride Lithium Chloride Complex Solution, 1.0 M In Thf is a highly reactive organometallic reagent used as a powerful nucleophile and base in advanced synthetic chemistry. This solution is critical for enabling challenging carbon-carbon bond formation and functional group transformations under mild conditions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Facilitates Negishi cross-coupling reactions for the formation of C-C bonds in complex organic molecules.
• Employed in the preparation of specialty chemicals and fine chemicals requiring sterically hindered transformations.
• Useful in polymer chemistry for initiating or modifying polymerization processes to create advanced materials.
• Acts as a strong, non-nucleophilic base for deprotonation reactions in sensitive synthetic sequences.
• Applied in materials science research for the surface functionalization of nanoparticles and other substrates.
• Enables the synthesis of natural products and complex heterocyclic compounds in academic and industrial R&D.

Basic Information

Product Name	2,2,6,6-Tetramethylpiperidinylzinc Chloride Lithium Chloride Complex Solution, 1.0 M In Thf
CAS No.	1145881-09-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2,2,6,6-Tetramethylpiperidin-1-ylzinc Chloride Lithium Chloride Complex; TMP-ZnCl·LiCl; (2,2,6,6-Tetramethylpiperidin-1-yl)zinc Chloride Lithium Chloride Adduct; Zinc, chloro(2,2,6,6-tetramethyl-1-piperidinyl)-, compd. with lithium chloride (1:1); TMPZnCl·LiCl; Lithium Chloride Complex of 2,2,6,6-Tetramethylpiperidinylzinc Chloride; Sterically Hindered Zinc Amide Base; Tetramethylpiperidinozinc Chloride Lithium Chloride Complex
EINECS	Contact for details

Quality Control

Every batch of our 2,2,6,6-Tetramethylpiperidinylzinc Chloride Lithium Chloride Complex Solution is manufactured and tested under stringent quality management systems. We ensure high lot-to-lot consistency and precise molarity through rigorous analytical controls, including titration and spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing assay, purity, and solvent content is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C (refrigerated) to maintain stability and potency. This product is highly volatile and easily oxidized; ensure containers are kept sealed and only handled in a controlled, moisture-free environment. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow solution
Concentration	1.0 M in Tetrahydrofuran (THF)
Assay (Titration)	0.95 - 1.05 M
Identification (IR)	Conforms to structure
Water Content (KF)	< 100 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.