Description

6-(4-Phenylpiperazin-1-yl)-3-(propan-2-yl)[1,2,4]triazolo[4,3-b]pyridazine is a high-purity, heterocyclic organic compound featuring a fused triazolopyridazine core. This advanced pharmaceutical intermediate is critical for research and development in medicinal chemistry, offering a versatile scaffold for creating novel bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of potential therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Biochemical Tool Compound: Employed in vitro to study specific enzyme inhibition or receptor modulation pathways.
• Process Chemistry Development: Utilized for scaling up synthetic routes and optimizing manufacturing processes for active pharmaceutical ingredients (APIs).
• Academic Research: Applied in university and institutional labs for fundamental research in heterocyclic chemistry and drug discovery.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting the drug development pipelines of larger pharmaceutical companies.

Basic Information

Item	Detail
Product Name	6-(4-Phenylpiperazin-1-yl)-3-(propan-2-yl)[1,2,4]triazolo[4,3-b]pyridazine
CAS No.	1144495-53-3
Molecular Formula	C18H22N6
Molecular Weight	322.41 g/mol
Synonyms	6-(4-Phenyl-1-piperazinyl)-3-isopropyl-[1,2,4]triazolo[4,3-b]pyridazine; 3-Isopropyl-6-(4-phenylpiperazin-1-yl)-[1,2,4]triazolo[4,3-b]pyridazine; 1144495-53-3; 6-(4-Phenylpiperazin-1-yl)-3-(1-methylethyl)-[1,2,4]triazolo[4,3-b]pyridazine; Triazolopyridazine derivative CAS 1144495-53-3
EINECS	Contact for details

Quality Control

Every batch of 6-(4-Phenylpiperazin-1-yl)-3-(propan-2-yl)[1,2,4]triazolo[4,3-b]pyridazine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for critical R&D and scale-up work. A Certificate of Analysis (COA) detailing specifications and results from advanced analytical techniques (HPLC, NMR, MS) is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.