Description

n-(4-Chlorobenzyl)-1-([1,2,4]Triazolo[4,3-B]Pyridazin-6-Yl)Piperidine-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1144462-88-3. This compound is a critical building block in modern medicinal chemistry, valued for its complex heterocyclic structure which serves as a key scaffold in drug discovery. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly within oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) targeting specific biological pathways.
• Drug Discovery & Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in research laboratories.
• Oncology Research: Used in the development of potential kinase inhibitors and other targeted cancer therapies due to its triazolopyridazine core.
• CNS Drug Development: Investigated as a building block for compounds intended to cross the blood-brain barrier for neurological applications.
• Biochemical Research: Employed as a reference standard or a tool compound in high-throughput screening and biochemical assays.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex molecules for clinical trials.

Basic Information

Product Name	n-(4-Chlorobenzyl)-1-([1,2,4]Triazolo[4,3-B]Pyridazin-6-Yl)Piperidine-3-Carboxamide
CAS No.	1144462-88-3
Molecular Formula	C19H18ClN7O
Molecular Weight	395.84 g/mol
Synonyms	1-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)-N-[(4-chlorophenyl)methyl]piperidine-3-carboxamide; N-(4-Chlorobenzyl)-1-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidine-3-carboxamide; 1144462-88-3; UNII-8K7I2K3P0H; 8K7I2K3P0H; CHEMBL3186666; AKOS025147324; BDBM50389357.
EINECS	Contact for details

Quality Control

Our n-(4-Chlorobenzyl)-1-([1,2,4]Triazolo[4,3-B]Pyridazin-6-Yl)Piperidine-3-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.