Description

1-(3-Methyl-[1,2,4]Triazolo[4,3-B]Pyridazin-6-Yl)Piperidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a sophisticated heterocyclic scaffold for targeted drug discovery. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in areas requiring complex nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a core scaffold in structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• API Development: Integral in the development and scale-up processes for new active pharmaceutical ingredients requiring fused triazolopyridazine motifs.
• Biochemical Tool Compound: May be utilized in biochemical assays and as a reference standard for pharmacological studies.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	1-(3-Methyl-[1,2,4]Triazolo[4,3-B]Pyridazin-6-Yl)Piperidine-3-Carboxylic Acid
CAS No.	1144452-93-6
Molecular Formula	C13H16N6O2
Molecular Weight	288.31 g/mol
Synonyms	1-(3-Methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidine-3-carboxylic acid; 3-Methyl-6-(3-piperidinecarboxylic acid)-[1,2,4]triazolo[4,3-b]pyridazine; 6-(3-Carboxypiperidin-1-yl)-3-methyl-[1,2,4]triazolo[4,3-b]pyridazine; Piperidine-3-carboxylic acid, 1-(3-methyl[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-; CAS 1144452-93-6
EINECS	Contact for details

Quality Control

Our 1-(3-Methyl-[1,2,4]Triazolo[4,3-B]Pyridazin-6-Yl)Piperidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research-grade and pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.