Description

n-[2-(4-Fluorophenyl)Ethyl]-1-[3-(Trifluoromethyl)[1,2,4]Triazolo[4,3-B]Pyridazin-6-Yl]Piperidine-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate designed for research and development. This compound is critical for medicinal chemistry programs targeting novel therapeutic agents, particularly in the central nervous system (CNS) and oncology spaces. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers requiring a reliable supply of complex heterocyclic building blocks.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of new active pharmaceutical ingredients (APIs), especially for CNS-targeting drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel drug candidates.
• Biochemical Tool Compound: Acts as a reference standard or probe in pharmacological assays to study specific biological pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up synthesis under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for cutting-edge research in organic synthesis and drug discovery.

Basic Information

Product Name	n-[2-(4-Fluorophenyl)Ethyl]-1-[3-(Trifluoromethyl)[1,2,4]Triazolo[4,3-B]Pyridazin-6-Yl]Piperidine-3-Carboxamide
CAS No.	1144430-89-6
Molecular Formula	C22H20F4N6O
Molecular Weight	460.43 g/mol
Synonyms	1-[3-(Trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]-N-[2-(4-fluorophenyl)ethyl]piperidine-3-carboxamide; 1144430-89-6; UNII-1Q9F0V8Q8J; 1Q9F0V8Q8J; CHEMBL3186666; BDBM50157857; AKOS025147064; ZINC000095515756; 6-[3-[(2-(4-Fluorophenyl)ethyl)carbamoyl]piperidin-1-yl]-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine
EINECS	Contact for details

Quality Control

Our n-[2-(4-Fluorophenyl)Ethyl]-1-[3-(Trifluoromethyl)[1,2,4]Triazolo[4,3-B]Pyridazin-6-Yl]Piperidine-3-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research-grade and cGMP standards where applicable. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.