Description

(S)-7-(Trifluoromethyl)Chroman-4-Amine is a high-purity chiral amine building block featuring a chroman scaffold and a trifluoromethyl group. This compound is of significant value in pharmaceutical research and development due to its structural complexity and the desirable properties imparted by the fluorine atoms, such as enhanced metabolic stability and membrane permeability. It is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Key chiral intermediate in the synthesis of pharmaceutical candidates targeting central nervous system (CNS) disorders.
• Building block for the development of agrochemicals, including herbicides and fungicides.
• Precursor in the research of bioactive molecules with potential anti-inflammatory or antimicrobial properties.
• Versatile scaffold for constructing compound libraries in high-throughput screening and drug discovery programs.
• Used in asymmetric synthesis and catalysis studies due to its defined stereochemistry.
• Intermediate for the preparation of more complex fluorinated organic molecules.

Basic Information

Product Name	(S)-7-(Trifluoromethyl)Chroman-4-Amine
CAS No.	1140496-05-4
Molecular Formula	C10H10F3NO
Molecular Weight	217.19 g/mol
Synonyms	(4S)-7-(Trifluoromethyl)-3,4-dihydro-2H-1-benzopyran-4-amine; (S)-7-(Trifluoromethyl)-3,4-dihydro-2H-chromen-4-amine; (S)-7-(Trifluoromethyl)chroman-4-amine; 4-Amino-7-(trifluoromethyl)chroman, (S)-; 1140496-05-4; (S)-4-Amino-7-(trifluoromethyl)chroman; 7-(Trifluoromethyl)chroman-4-amine, (S)-
EINECS	Contact for details

Quality Control

Our (S)-7-(Trifluoromethyl)Chroman-4-Amine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive analytical data, including chiral purity (enantiomeric excess) verification. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with every batch to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.