Description

4-Bromo-3-Fluoro-2-Methoxyaniline is a high-purity, multi-functional aromatic amine building block of significant importance in advanced organic synthesis. Its unique halogenated and methoxylated structure makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the bromo and fluoro substituents enhance biological activity and environmental stability.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Employed in the synthesis of complex, high-performance dyes and pigments due to its aniline core and halogen substituents.
• Cross-Coupling Reactions: An essential substrate for palladium-catalyzed reactions like Suzuki, Buchwald-Hartwig, and Ullmann couplings to create biaryl and other complex structures.
• Chemical Biology & Proteomics: Utilized as a building block for designing molecular probes, enzyme inhibitors, and other tools for biochemical research.

Basic Information

Item	Detail
Product Name	4-Bromo-3-Fluoro-2-Methoxyaniline
CAS No.	1137869-95-4
Molecular Formula	C7H7BrFNO
Molecular Weight	220.04 g/mol
Synonyms	2-Methoxy-4-bromo-3-fluoroaniline; 3-Fluoro-4-bromo-2-methoxyaniline; 4-Bromo-3-fluoro-o-anisidine; 2-Amino-5-bromo-6-fluoroanisole; 5-Bromo-6-fluoro-2-methoxyaniline; Benzenamine, 4-bromo-3-fluoro-2-methoxy-; 4-Bromo-3-fluoro-2-methoxybenzenamine
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Fluoro-2-Methoxyaniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This amine derivative is light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent oxidation. Keep away from strong acids, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC Area %)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.