Description

(2-Chloro-5-Nitrophenyl)Methanamine Hydrochloride is a high-purity organic intermediate with significant utility in advanced chemical synthesis. Its value lies in its role as a versatile building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research institutions and industrial manufacturers engaged in the synthesis of heterocyclic compounds, dyes, and functional materials, where precise chemical functionality is critical.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and pesticides, leveraging its nitro and chloro substituents for bioactivity.
• Dye and Pigment Manufacturing: Serves as a precursor for azo dyes and other complex colorants, contributing to color fastness and specific hue properties.
• Material Science Research: Employed in the creation of organic semiconductors, liquid crystals, and polymers requiring specific electron-withdrawing groups.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new reaction pathways and catalytic processes.
• Custom Synthesis: Provides a foundational structure for contract manufacturing organizations (CMOs) producing bespoke chemicals for client-specific applications.

Basic Information

Product Name	(2-Chloro-5-Nitrophenyl)Methanamine Hydrochloride
CAS No.	1135021-79-2
Molecular Formula	C7H8ClN2O2 • HCl
Molecular Weight	237.06 g/mol (Free base: 200.61 g/mol)
Synonyms	1-(2-Chloro-5-nitrophenyl)methanamine hydrochloride; (2-Chloro-5-nitrobenzyl)amine hydrochloride; 2-Chloro-5-nitrobenzylamine hydrochloride; α-Amino-2-chloro-5-nitro toluene hydrochloride; Benzenemethanamine, 2-chloro-5-nitro-, hydrochloride; 2-Chloro-5-nitro-1-benzylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (2-Chloro-5-Nitrophenyl)Methanamine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting critical parameters such as assay, impurity profile, and residual solvents. Our quality commitment aligns with cGMP principles where applicable, supporting our clients' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.