Description

2H-1-Benzopyran-2-One, 6-Fluoro-3,4-Dihydro-4-Phenyl- is a high-purity, fluorinated coumarin derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel active molecules. It is primarily required by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and material science industries seeking to incorporate its unique fluorinated chromone structure into new chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the bioactivity of the coumarin scaffold.
• Agrochemical Research: Used as a building block for developing new pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental stability.
• Fluorescent Probe Synthesis: Serves as a core structure for creating specialized fluorescent dyes and molecular probes used in biochemical assays and diagnostic imaging.
• Organic Electronic Materials: Investigated as a component in the development of organic light-emitting diodes (OLEDs) and other optoelectronic materials.
• Academic & Industrial R&D: Employed in methodological chemistry research for studying fluorination reactions and heterocyclic compound synthesis.
• Fine Chemical Synthesis: A versatile intermediate for creating complex, value-added specialty chemicals for various high-tech applications.

Basic Information

Product Name	2H-1-Benzopyran-2-One, 6-Fluoro-3,4-Dihydro-4-Phenyl-
CAS No.	1134885-95-2
Molecular Formula	C15H11FO2
Molecular Weight	242.25 g/mol
Synonyms	6-Fluoro-3,4-dihydro-4-phenylcoumarin; 6-Fluoro-4-phenylchroman-2-one; 4-Phenyl-6-fluorochroman-2-one; 6-Fluoro-4-phenyl-3,4-dihydro-2H-chromen-2-one; 6-Fluoro-4-phenyl-3,4-dihydro-2H-1-benzopyran-2-one; Fluorinated dihydrocoumarin derivative; 1134885-95-2
EINECS	Contact for details

Quality Control

Every batch of 2H-1-Benzopyran-2-One, 6-Fluoro-3,4-Dihydro-4-Phenyl- undergoes rigorous analytical testing to ensure it meets the stringent purity requirements for pharmaceutical and advanced research applications. Our quality assurance protocols are designed to guarantee batch-to-batch consistency and traceability. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.