Description

trans-2-(2-Methylthiobenzoyl)Cyclohexane-1-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and functional groups. This compound is critical for the synthesis of complex organic molecules, offering a precise building block for research and development in medicinal chemistry. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of potential drug candidates, particularly in therapeutic areas requiring complex molecular architectures.
• Medicinal Chemistry Research: Serves as a crucial scaffold for structure-activity relationship (SAR) studies and the exploration of new chemical entities in academic and industrial R&D settings.
• Process Chemistry Development: Used in the optimization and scale-up of synthetic routes for target molecules during pre-clinical and clinical development phases.
• Fine Chemical Synthesis: Employed in the custom synthesis of specialty chemicals, agrochemical intermediates, and other high-value organic compounds requiring its unique benzoyl-cyclohexane carboxylic acid framework.

Basic Information

Product Name	trans-2-(2-Methylthiobenzoyl)Cyclohexane-1-Carboxylic Acid
CAS No.	1134611-70-3
Molecular Formula	C15H18O3S
Molecular Weight	278.37 g/mol
Synonyms	(1R,2R)-2-(2-Methylsulfanylbenzoyl)cyclohexane-1-carboxylic acid; (1R,2R)-2-(2-(Methylthio)benzoyl)cyclohexanecarboxylic acid; trans-2-(2-(Methylthio)benzoyl)cyclohexanecarboxylic Acid; 2-(2-Methylthiobenzoyl)cyclohexanecarboxylic Acid; (trans)-2-(2-Methylthiobenzoyl)cyclohexane-1-carboxylic Acid; 1134611-70-3; 2-(2-Methylmercaptobenzoyl)cyclohexanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our production of trans-2-(2-Methylthiobenzoyl)Cyclohexane-1-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (trans isomer)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.