Description

3-Bromo-4-(1H-Tetrazol-5-Yl)Benzoic Acid is a high-value, multifunctional heterocyclic building block that combines a benzoic acid core with bromo and tetrazole substituents. This compound is critical for advanced pharmaceutical research and agrochemical development, serving as a key intermediate in the synthesis of active ingredients and functional materials. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A versatile synthon for the development of novel drug candidates, particularly in areas like enzyme inhibitors and receptor modulators where the tetrazole moiety acts as a bioisostere for carboxylic acids.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its unique halogenated aromatic structure.
• Material Science Research: Serves as a precursor for functional polymers, metal-organic frameworks (MOFs), and ligands for catalysis due to its coordinating tetrazole group and reactive bromine site.
• Chemical Biology & Proteomics: Employed as a building block for activity-based probes and photoaffinity labels, exploiting the reactivity of the bromine atom for further functionalization.
• Coordination Chemistry: Acts as a polydentate ligand for transition metals, useful in creating catalysts with specific geometric and electronic properties.

Basic Information

Product Name	3-Bromo-4-(1H-Tetrazol-5-Yl)Benzoic Acid
CAS No.	1131615-11-6
Molecular Formula	C8H5BrN4O2
Molecular Weight	269.06 g/mol
Synonyms	5-(3-Bromo-4-carboxyphenyl)-1H-tetrazole; 3-Bromo-4-(1H-tetrazol-5-yl)benzoic acid; 3-Bromo-4-(2H-tetrazol-5-yl)benzoic acid; Benzoic acid, 3-bromo-4-(1H-tetrazol-5-yl)-; 3-Bromo-4-(tetrazol-5-yl)benzoic acid; 4-(1H-Tetrazol-5-yl)-3-bromobenzoic acid; 3-Bromo-4-(1H-1,2,3,4-tetrazol-5-yl)benzoic acid
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-(1H-Tetrazol-5-Yl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support development projects with custom purity grades and analytical method development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if possible to prevent degradation. Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (HPLC)	≥98.0% / ≥99.0% (High Purity Grades Available)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.