Description

3-Bromo-4-(Difluoromethyl)Benzoic Acid is a high-purity, multi-functional aromatic carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and difluoromethyl substituents, makes it an exceptionally valuable intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the difluoromethyl group can enhance bioavailability and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of specialized fluorinated organic compounds for electronic displays and optoelectronic devices.
• Polymer Chemistry: Employed as a monomer or modifier to introduce halogen and fluorine functionalities into polymers, altering their physical and chemical properties.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	3-Bromo-4-(Difluoromethyl)Benzoic Acid
CAS No.	1131615-04-7
Molecular Formula	C8H5BrF2O2
Molecular Weight	251.03 g/mol
Synonyms	4-(Difluoromethyl)-3-bromobenzoic acid; 3-Bromo-4-(difluoromethyl)benzoic acid; Benzoic acid, 3-bromo-4-(difluoromethyl)-; 2-Bromo-α,α-difluoro-4-carboxytoluene; 3-Bromo-α,α-difluoro-p-toluic acid; CAS 1131615-04-7
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-4-(Difluoromethyl)Benzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is available for each lot, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.