Description

3-Chloro-5-Fluorobenzene-1-Sulfonyl Chloride is a high-purity, multi-functional chemical intermediate essential for advanced organic synthesis. This compound is valued for its dual reactive sites, enabling its use as a key building block in the development of complex molecules. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing sulfonamides and other sulfonyl-based derivatives.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require the sulfonyl chloride functional group.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers and advanced materials.
• Chemical Research: Employed in academic and industrial R&D for exploring new reaction pathways and creating compound libraries for screening.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of specialized colorants and functional dyes.

Basic Information

Product Name	3-Chloro-5-Fluorobenzene-1-Sulfonyl Chloride
CAS No.	1131397-73-3
Molecular Formula	C6H3Cl2FO2S
Molecular Weight	229.06 g/mol
Synonyms	3-Chloro-5-fluorobenzenesulfonyl chloride; 1-Chloro-3-fluoro-5-(chlorosulfonyl)benzene; 3-Chloro-5-fluorophenylsulfonyl chloride; 5-Chloro-3-fluorobenzenesulfonyl chloride; Benzenesulfonyl chloride, 3-chloro-5-fluoro-; 3-Cl-5-F-PhSO2Cl
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Fluorobenzene-1-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if possible. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.