Description

6-Bromo-2-(Trimethylsilyl)Furo[3,2-B]Pyridine is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound is particularly significant for its role as a key intermediate in the development of complex pharmaceutical and agrochemical molecules. It is primarily needed by research scientists and process chemists in the pharmaceutical, agrochemical, and material science industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its unique fused-ring structure.
• Material Science Precursor: Serves as a specialized monomer or precursor for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to form complex biaryl systems.
• Ligand Synthesis: Utilized in the preparation of novel nitrogen-containing ligands for catalysis and coordination chemistry.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	6-Bromo-2-(Trimethylsilyl)Furo[3,2-B]Pyridine
CAS No.	1131335-72-2
Molecular Formula	C12H16BrNOSi
Molecular Weight	314.25 g/mol
Synonyms	6-Bromo-2-(trimethylsilyl)furo[3,2-b]pyridine; 2-(Trimethylsilyl)-6-bromofuro[3,2-b]pyridine; Furo[3,2-b]pyridine, 6-bromo-2-(trimethylsilyl)-; 6-Bromo-2-trimethylsilylfuro[3,2-b]pyridine; 1131335-72-2; 6-Bromo-2-TMS-furo[3,2-b]pyridine
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-(Trimethylsilyl)Furo[3,2-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.